Publications
Zheng Y., Gu Z, Shudde C.E., Piper T.L., Wang X., Aleck G.A., Zhou J., King D., Chanda M.K., Trinch L., Zou W., Courtney A.H., An engineered viral protein activates STAT5 to prevent T cell suppression. Science Immunology. 2025, 10(107) eadn9633.
#Chanda, M.K., #Shudde, E.S., Piper, T.L., Zhang, Y., Courtney, A.H., Combined analysis of T cell activation and T cell-mediated cytotoxicity by imaging cytometry. Journal of Immunological Methods. 2022, 506:113290. #Equal contribution
*Courtney, A.H., Shvets, A., Lu, W., Griffante, G., Mollenauer, M., Horkova, V., Lo, W.L., Yu, S., Stepanek, O., Chakraborty A.K., *Weiss, A., CD45 functions as a signaling gatekeeper in T cells. Science Signaling. 2019, 12, eaaw8151.
*Corresponding author, F1000 featured article
Courtney, A.H., Lo, W.L., Weiss, A., TCR Signaling: Mechanisms of initiation and propagation. Trends in Biochemical Sciences. 2018, 43 (2), 108-123.
Courtney, A.H., Amacher, J.A., Kadlecek, T.A., Mollenauer, M.N., Au-Yeung, B.B., Kuriyan, J., Weiss, A., A phosphosite within the SH2 domain of Lck regulates its activation by CD45. Molecular Cell. 2017, 67 (3), 498-511.
Manz, B.N., Tan, X.Y., Courtney, A.H., Rutaganira, F., Palmer, E., Shokat, K.M., Weiss, A., Small molecule inhibition of Csk alters affinity recognition by T cells. eLife. 2015, 4, e08088.
Bennett, N.R., Zwick, D.B., Courtney, A.H., Kiessling, L.L., Multivalent antigens for promoting B and T cell activation. ACS Chemical Biology. 2015, 10 (8), 1817-1824.
Courtney, A.H., Bennett, N.R., Zwick, D.B., Hudon, J., Kiessling, L.L., Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling. 2013, ACS Chemical Biology. 2014, 9 (1), 202-210.
Klim, J.R., Fowler, A. J., Courtney, A.H., Wrighton, P.J., Sheridan, R.T.C., Wong, M.L., Kiessling, L.L., A high affinity RGD-based peptidomemetic supports cell adhesion and activation of aVb3 integrins. ACS Chemical Biology. 2012, 7 (3), 518-525.
Li, L., Klim, J.R., Derda, R., Courtney, A.H., Kiessling, L.L., Spatial control of cell fate using synthetic surfaces to potentiate TGF-b signalling. Proceedings of the National Academy of Sciences USA. 2011, 108 (29), 11745-11750.
Highlighted in C&E News
Courtney, A.H., Puffer, E.B., Pontrello, J.K., Yang, Z.Q., Kiessling L.L., Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proceedings of the National Academy of Sciences USA. 2009, 106 (8), 2500-2505.
Highlighted in C&E News and ACS Chemical Biology
