© Courtney Lab ∣ University of Michigan

1150 W. Medical Center Dr.

MSRB III Room 2240 

Ann Arbor, MI 48109

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Publications

9. *Courtney, A.H., Shvets, A., Lu, W., Griffante, G., Mollenauer, M., Horkova, V., Lo, W.L., Yu, S., Stepanek, O., Chakraborty A.K., *Weiss, A., CD45 acts as a signaling gatekeeper in T cells. Science Signaling. 2019, 12, eaaw8151. *Corresponding author

(F1000 featured article)

8. Courtney, A.H., Lo, W.L., Weiss, A., TCR Signaling: Mechanisms of initiation and propagation. Trends in Biochemical Sciences. 2018, 43 (2), 108-123.

 

7. Courtney, A.H., Amacher, J.A., Kadlecek, T.A., Mollenauer, M.N., Au-Yeung, B.B., Kuriyan, J., Weiss, A., A phosphosite within the SH2 domain of Lck regulates its activation by CD45. Molecular Cell. 2017, 67 (3), 498-511.

 

6. Manz, B.N., Tan, X.Y., Courtney, A.H., Rutaganira, F., Palmer, E., Shokat, K.M., Weiss, A., Small molecule inhibition of Csk alters affinity recognition by T cells. eLife. 2015, 4, e08088. 

 

5. Bennett, N.R., Zwick, D.B., Courtney, A.H., Kiessling, L.L., Multivalent antigens for promoting B and T cell activation. ACS Chemical Biology. 2015, 10 (8), 1817-1824.

 

4. Courtney, A.H., Bennett, N.R., Zwick, D.B., Hudon, J., Kiessling, L.L., Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling. 2013, ACS Chemical Biology. 2014, 9 (1), 202-210.

 

3. Klim, J.R., Fowler, A. J., Courtney, A.H., Wrighton, P.J., Sheridan, R.T.C., Wong, M.L., Kiessling, L.L., A high affinity RGD-based peptidomemetic supports cell adhesion and activation of aVb3 integrins. ACS Chemical Biology. 2012, 7 (3), 518-525.

 

2. Li, L., Klim, J.R., Derda, R., Courtney, A.H., Kiessling, L.L., Spatial control of cell fate using synthetic surfaces to potentiate TGF-b signalling. Proceedings of the National Academy of Sciences USA. 2011, 108 (29), 11745-11750.

(Highlighted in C&E News)

 

1. Courtney, A.H., Puffer, E.B., Pontrello, J.K., Yang, Z.Q., Kiessling L.L., Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proceedings of the National Academy of Sciences USA. 2009, 106 (8), 2500-2505.

(Highlighted in C&E News and ACS Chemical Biology)